Does it ever get any better?

After years and years of all kinds of therapy and med cocktails, he's getting worse.  Does it ever get any better?  Or, am I just stuck with whatever the day holds?  DH has ADD with high anxiety.  Has been on meds and in therapy for too long.  Nothing is changing and in fact, is getting worse.  Not sure what to do or which direction to go next.  Any advice is appreciated.