when the pills wear off

I have noticed that when the pills my husband is taking for his ADD wear off (when it is about time for another dose) his ADD returns worse than ever. Perhaps, I am now used to the new improved person and what I'm seeing is the way he was previous to taking the pills.  It really does seem like his ADD is worse than ever without the pills, but drastically improved while the pills are in effect.  Has anyone else noticed this about their spouse?